NCATS-SM4420 (Compound A35) is an orally active thyroid-stimulating hormone receptor ( TSHR ) ligand that inhibits the proliferation of MDA-T32 and MDA-T85 cells in vitro ( IC 50 values of 0.71 μM and 0.38 μM, respectively) and suppresses metastasis of MDA-T85F1 in mice. NCATS-SM4420 holds promise for research in the field of thyroid cancer .
Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > TSH Receptor
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