T338C Src-IN-2 is a mutant c-Src kinase inhibitor, with an IC 50 of 317 nM against T338C c-Src , 57 nM against T338C/V323A c-Src , and 19 nM against T338C/V323S c-Src . T338C Src-IN-2 inhibits the kinase activity of endogenous cysteine gatekeeper MOK . T338C Src-IN-2 reduces global phosphotyrosine levels in v-Src-ES1-transformed NIH-3T3 cells.
Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > Src
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