Latrunculin A

Overview

Latrunculin A (LAT-A), found in the red sea sponge Latrunculia magnifica , is a G-actin polymerization inhibitor. Latrunculin A binds to actin monomers and inhibits polymerization of actin with K d s of 0.1, 0.4, 4.7 μM and 0.19 μM for ATP-actin, ADP-Pi-actin, ADP-actin and G-actin, respectively. Latrunculin A has effective anti-metastatic properties for cancer research. Latrunculin A blocks cell migration.

Application

Products | Products > Signaling Pathways > Cytoskeleton | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Arp2/3 Complex

Product Information

• Catalog No.: HY-16929
• CAS No.: 76343-93-6
• Molecular Formula: C22H31NO5S
• Molecular Weight: 421.55
• Purity: 98.9%
• Storage: Solution, -20°C, 2 years
• Availability: In-stock

Source

Original product source