Pan-Raf/RTK inhibitor 1 (compound I-16) is a potent pan-Raf inhibitor with IC 50 values of 3.49 nM (BRaf V600E ), 8.86 nM (ARaf), 5.78 nM (BRaf WT ), and 1.65 nM (CRaf). Pan-Raf/RTK inhibitor 1 exhibits antiproliferative activities against various cancer cell lines and can be utilized in cancer research.
Products | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Raf
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