BJP-07-017-3 is the inhibitor for proline cis trans isomerase ( Pin1 ) with an IC 50 of 9 nM. BJP-07-017-3 forms covalent bond with Cys113 of Pin1 , induces conformational changes in Pin1 , reduces its stability, and leads to a proteasome-dependently degradation.
Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > PIN1
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