A-86929

Overview

A-86929 is a highly potent and selective dopamine D 1 receptor agonist with a p K i value of 7.3. In the 6-OHDA ( HY-B1081 )-induced unilateral nigrostriatal lesion rat model, A-86929 significantly induces rotational behavior. It also improves motor function in the MPTP ( HY-15608 )-induced Parkinson's disease marmoset model. Additionally, A-86929 demonstrates potential therapeutic value in reducing cocaine-seeking behavior in rats and reversing Haloperidol ( HY-14538 )-induced cognitive deficits in rhesus monkeys. A-86929 can be used for research in neurological disorders.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Dopamine Receptor

Product Information

• Catalog No.: HY-171472
• CAS No.: 171961-95-8
• Molecular Formula: C18H21NO2S
• Molecular Weight: 315.43
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source