PI3Kδ/BET-IN-1 (compound 10b) shows excellent and balanced activities against PI3Kδ ( IC 50 = 112 nM) and BRD4-BD1 ( IC 50 = 19 nM) and exhibits strong antiproliferative activities in DLBCL cells.
Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > PI3K | Products > Signaling Pathways > Epigenetic Reader Domain
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