AX-53802

Overview

AX-53802 is a ferroptosis inducer targeting GPX4 with an IC 50 of 0.34 µM. AX-53802 forms a covalent bond with GPX4, initiating membrane translocation directly upon binding. AX-53802 and FAK/Src inhibitors promotes cell death. AX-53802 can be used for cancer study.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Glutathione Peroxidase | Products > Signaling Pathways > Ferroptosis

Product Information

• Catalog No.: HY-172761
• CAS No.: 1008482-71-0
• Molecular Formula: C23H21FN2O4
• Molecular Weight: 408.42
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source