PSF-IN-2 (Compound (C)-30) is a PSF inhibitor with an IC 50 value of 0.005 pM. PSF-IN-2 exhibits anti-cancer activity, and its IC 50 value for inhibiting the proliferation of 22Rv1 cells is 0.5 μM. PSF-IN-2 activates the p53 signaling pathway by inhibiting the binding of PSF to RNA, inducing the expression of related genes, promoting apoptosis , and inhibiting the cell cycle. PSF-IN-2 can be used in cancer research.
Products | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > MDM-2/p53
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