Galectin-3-IN-6

Galectin-3-IN-6
  • CAS No.:2604662-64-6
  • Grade:99.98%
  • Formula:C28H29Cl2F3N4O6
  • M.W.:645.45

Overview

Galectin-3-IN-6 is a human and murine galectin-3 ( Gal-3 ) inhibitor, with an IC 50 of 12 nM against human galectin-3 , an IC 50 of 12.6 nM against mutant murine galectin-3 (V160A), and a K d of 13 nM for human galectin-3 , as well as oral bioavailability. Galectin-3-IN-6 reduces the levels of liver fibrosis markers type I collagen and α-smooth muscle actin in mouse models of acute liver injury and fibrosis. Galectin-3-IN-6 can be used for the research of acute liver injury and fibrosis.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Cardiovascular Disease | Products > Research Areas > Cancer | Products > Signaling Pathways > Galectin

Product Information

  • Catalog No.: HY-173235
  • CAS No.: 2604662-64-6
  • Molecular Formula: C28H29Cl2F3N4O6
  • Molecular Weight: 645.45
  • Purity: 99.98%
  • Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source


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