LC-PDin06 is a selective PRDX1 inhibitor with an IC 50 of 0.042 μM. LC-PDin06, a Celastrol ( HY-13067 ) derivative, shows potent antiproliferative activity against colorectal cancer cells by significantly increasing ROS levels.
Products | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Reactive Oxygen Species (ROS)
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