BER-5

Overview

BER-5 is a potent MrgX2 antagonist. BER-5 possess broad-spectrum antagonistic activity against a diverse range of MrgX2 agonists. BER-5 can inhibit Substance P (SP) ( HY-P0201 )-induced degranulation of LAD2 cells. BER-5 attenuates SP-induced allergic reactions in mice. BER-5 can be used for the study of allergic reactions.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Mas-related G-protein-coupled Receptor (MRGPR) | Products > Signaling Pathways > Interleukin Related | Products > Signaling Pathways > Calcium Channel

Product Information

• Catalog No.: HY-174452
• CAS No.: 724709-67-5
• Molecular Formula: C20H16O4
• Molecular Weight: 320.34
• Purity: 99.83%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 5 mg/mL (15.61 mM); Clear solution
• Availability: In-stock

Source

Original product source