GABA receptor antagonist 2 (Compound IId) is a GABA receptor antagonist with a LC 50 of 0.0735 μg/mL for Plutella xylostella ( P. xylostella ). GABA receptor antagonist 2 has significant insecticidal activities against P. xylostella and its resistant strain, and Spodoptera frugiperda , and Chilo suppressalis . GABA receptor antagonist 2 binds the GABA receptor at the site of Drosophila Rdl G335 . GABA receptor antagonist 2 can be used to manage resistant pest populations.
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