ADAR1-IN-1 is a potent ADAR1 inhibitor. ADAR1-IN-1 significantly suppressed DU-145 cell proliferation ( IC 50 = 1.11 μM), clonogenicity, migration, and invasion, arrests cell cycle, and induces apoptosis . ADAR1-IN-1 safely and effectively inhibits tumor growth. ADAR1-IN-1 can be used for the study of prostate cancer (PCa).
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