UNC9750 is an inositol phosphate multikinase ( IPMK ) inhibitor with IC 50 values of 31.6 and 374 nM for IPMK and IP6K2 , respectively.. UNC9750 inhibits cellular accumulation of InsP 5 , the direct product of IPMK kinase activity, while having no effect on either InsP 6 or InsP 7 levels. UNC9750 has ≥ 75% inhibition of four kinases ( DAPK1 , DYRK1B , PDGFR , and KDR ). UNC9750 can be used for the study of glioblastoma.
Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > DAPK | Products > Signaling Pathways > DYRK | Products > Signaling Pathways > PDGFR | Products > Signaling Pathways > IPK Superfamily
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