SOS1-IN-22 is a son of sevenless homolog 1 ( SOS1 ) inhibitor. SOS1-IN-22 can inhibit KRAS-G12C/SOS1 complex formation with an IC 50 value of 40.28 nM. SOS1-IN-22 can reduce phosphorylation ERK levels. SOS1-IN-22 can be used for the research of cancer , such as pancreatic carcinoma and appendiceal carcinoma.
Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > SOS1 | Products > Signaling Pathways > PERK
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