HEAL-116 is a potent, specific and orally active 3β-hydroxysteroid dehydrogenase type 1 ( 3βHSD1 ) inhibitor with an IC 50 of 1.18 μM and a K D of 1.32 μM. HEAL-116 inhibits DHEA ( HY-14650 ) metabolism and DHEA -induced target gene expression and cell proliferation. HEAL-116 can be used for cancer research, such as prostate cancer .
Products | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > 3β-HSD
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