NSC20116 is a uracil derivative that specifically targets the Set-and-Ring (SRA) domain of the oncogene UHRF1 . NSC20116 binds to the 5-methylcytosine (5mC) ( HY-W008091 ) recognition pocket of UHRF1 SRA domain, with a dissociation constant ( K d ) of 362 nM. NSC20116 can be used for the study of cancer .
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