Transthyretin-IN-4 (Compound B26) is a bivalent inhibitor of transthyretin ( TTR ) amyloidosis ( bIC 50 : 0.09 µM, pIC 50 : 1.4 µM). Transthyretin-IN-4 is used in the study of fatal heart failure with preserved ejection fraction (HFpEF) and fatal arrhythmias.
Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Transthyretin (TTR)
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