CALR ligand 1 (Compound 2a) is a calreticulin ( CALR ) ligand. CALR ligand 1 shows antitumor activity against triple-negative breast cancer (TNBC) cells ( IC 50 =0.1 μM). CALR ligand 1 induces intracellular calcium overloading and triggers apoptosis in TNBC cells. CALR ligand 1 is promising for research of TNBC .
Products | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Apoptosis
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