AMPA receptor modulator-10

Overview

AMPA receptor modulator-10 (Compound 9a) is an orally active AMPA receptor ( AMPAR ) positive allosteric modulator. AMPA receptor modulator-10 exhibits potent activity ( pEC 50 = 5.0) on the GluA2 subtype of AMPAR, significantly enhancing glutamate-induced calcium influx and current responses. AMPA receptor modulator-10 can reverse the memory impairment induced by Scopolamine (HY-N0296) and enhance cognitive function. AMPA receptor modulator-10 can be used for the research of neurological disease , such as schizophrenia.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Schizophrenia | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > iGluR

Product Information

• Catalog No.: HY-177873
• CAS No.: 620940-01-4
• Molecular Formula: C19H20F3N3O
• Molecular Weight: 363.38
• Purity: 98.78%
• Storage: 4°C, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
• Availability: In-stock

Source

Original product source