EP4 receptor antagonist 8

Overview

EP4 receptor antagonist 8 is an orally active EP4 antagonist (human EP4 IC 50 = 6.40 nM). EP4 receptor antagonist 8 significantly reduced paw and joint swelling, inflammatory cell infiltration, cartilage damage, pannus formation, and joint bone erosion in arthritis (AIA) mice in a dose-dependent manner. EP4 receptor antagonist 8 can be used for the study of inflammatory pain.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Neurological Disease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Prostaglandin Receptor | Products > Signaling Pathways > Interleukin Related

Product Information

• Catalog No.: HY-178465
• CAS No.: 3068255-86-4
• Molecular Formula: C26H21ClN6O4
• Molecular Weight: 516.94
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source