5-HT2CR agonist 2 (Compound 16k) is a selective, blood-brain barrier-penetrating and Gq-biased 5-HT 2C R agonist, with an EC 50 of 36 nM. 5-HT2CR agonist 2 attenuates MK801 ( HY-15084B )-induced hyperlocomotion and reverses Phencyclidine-induced hyperlocomotor activity.
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > 5-HT Receptor
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