Carba1 is a bifunctional Carbazole (HY-D0204) derivative that activates nicotinamide phosphoribosyltransferase ( NAMPT ) and enhances NAD biosynthesis. Carba1 binds to colchicine site of tubulin , enhancing the anti-tumor effect of various chemotherapy drugs, such as Paclitaxel ( HY-B0015 ). Carba1 exerts neuroprotective effect and can regulate cell energy metabolism. Carba1 can be used for the researches of cancer and chemotherapy-induced peripheral neuropathy (CIPN).
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