TAC 363

Overview

TAC 363 is a selective tachykinin NK-2 receptor antagonist. TAC 363 shows a rightward shift in the contractile response curve induced by Neurokinin A ( HY-P0197 ) with a pA 2 of 9.82. TAC 363 has a weak antagonistic effect on NK-1 receptors . TAC 363 can inhibit Neurokinin A -induced bronchoconstriction in guinea pigs with an ED 50 of 0.3 mg/kg. TAC 363 can be used for the research of bronchial asthma.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Respiratory Disease | Products > Disease Areas > Lower Respiratory Inflammation | Products > Disease Areas > Respiratory Inflammation | Products > Disease Areas > Asthma | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Neurokinin Receptor

Product Information

• Catalog No.: HY-180376
• CAS No.: 172081-08-2
• Molecular Formula: C38H48N8O6
• Molecular Weight: 712.84
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source