ORF 17910 is a potent, long-acting, orally active histamine H2 receptor antagonist. ORF 17910 exhibits significant and prolonged acid-suppressing activity in dogs and rats. However, the cardiac depressant effect of ORF 17910 cannot be completely overcome at high concentrations. ORF 17910 may be used to study diseases such as gastric ulcers.
Products | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Gastric Disease | Products > Disease Areas > Peptic Ulcer Disease | Products > Disease Areas > Gastric Ulcer | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Histamine Receptor
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