SU0383 is a dual MTH1 and OGG1 inhibitor with IC 50 values of 0.034 μM and 0.49 μM, respectively. SU0383 induces cytotoxicity in cancer cells and increases sensitivity of tumor cells to oxidative stress, and showing low toxicity in normal cells. SU0383 can be used for cancer research.
Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > DNA/RNA Synthesis
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