5-HT2CR modulator 1 (Compound 3B) is a selective, positive ago-allosteric modulator of 5HT 2C R with an EC 50 of 8 nM. 5-HT2CR modulator 1 is also a selective 5HT 2C R agonist with an EC 50 of 25 nM. 5-HT2CR modulator 1 reduces food intake.
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