CHI3L1-IN-5

Overview

CHI3L1-IN-5 (Compound Z17) is a highly selective CHI3L1 inhibitor with a K D value of 6 μM. CHI3L1-IN-5 restores the clearance ability of astrocytes by rejuvenating lysosomal function and Aβ uptake. CHI3L1-IN-5 alleviates neuroinflammation by inhibiting the NF-κB pathway. CHI3L1-IN-5 can be used for research on Alzheimer's disease.

Application

Products | Products > Disease Areas > Alzheimer's Disease | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Neurodegenerative Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > NF-κB | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Glycosidase | Products > Signaling Pathways > Amyloid-β | Products > Signaling Pathways > NF-κB

Product Information

• Catalog No.: HY-180899
• CAS No.: 2249043-42-1
• Molecular Formula: C19H22FN3O2
• Molecular Weight: 343.40
• Purity: 98.60%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Availability: In-stock

Source

Original product source