TPKI-39

TPKI-39
  • CAS No.:1005781-50-9
  • Grade:99.98%
  • Formula:C19H15N5O2
  • M.W.:345.35

Important Notice

  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
  3. The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

Overview

TPKI-39 is a DDR1 , DDR2 , and FLT1 inhibitor, with a human DDR1 IC 50 of 380 nM, human DDR1 K a of 24 nM, human DDR2 IC 50 of 120 nM, human FLT1 IC 50 of 65 nM, and human FLT1 K a of 91 nM.TPKI-39 inhibits DDR1 enzymatic activity and autophosphorylation, DDR2 enzymatic activity, and FLT1 enzymatic activity in cells.TPKI-39 inhibits collagen-induced DDR1 autophosphorylation in cells.

Application

Products | Products > Disease Areas > Others | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Others | Products > Signaling Pathways > Discoidin Domain Receptor

Product Information

  • Catalog No.: HY-181754
  • CAS No.: 1005781-50-9
  • Molecular Formula: C19H15N5O2
  • Molecular Weight: 345.35
  • Purity: 99.98%
  • Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source


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