Zorifertinib hydrochloride

Overview

Zorifertinib (AZD3759) hydrochloride is a potent, orally active, BBB-penetrant, EGFR inhibitor ( IC 50 s: 0.3, 0.2, and 0.2 nM for EGFR wt , EGFR L858R , and EGFR exon 19Del , respectively). Zorifertinib hydrochloride induces cancer cell apoptosis . Zorifertinib hydrochloride has antitumor activity, and can be used for NSCLC, HCC etc. research.

Application

Products | Products > Disease Areas > Respiratory Cancer | Products > Disease Areas > Non-Small Cell Lung Cancer | Products > Disease Areas > Cancer | Products > Disease Areas > Respiratory Disease | Products > Disease Areas > Lung Cancer | Products > Signaling Pathways > JAK/STAT Signaling | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > EGFR | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-18750A
• CAS No.: 1626387-81-2
• Molecular Formula: C22H24Cl2FN5O3
• Molecular Weight: 496.36
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source