WAY-100289 is an orally active antagonist for 5-HT3 receptor , that exhibits high affinity to the isolated rat vagus nerves with pA 2 of 8.9. WAY-100289 inhibits the Bezold-Jarisch reflex in anesthetized and awake rats.
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > 5-HT Receptor
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