ML289

Overview

ML289 (VU0463597) is a potent, selective, and CNS-penetrant mGlu3 ( IC 50 =0.66 μM) negative allosteric modulator. ML289 displays >15-fold selectivity over mGlu2 and is inactive against mGlu5. ML289 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Application

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Product Information

• Catalog No.: HY-19630
• CAS No.: 1382481-79-9
• Molecular Formula: C22H23NO3
• Molecular Weight: 349.42
• Purity: 98.29%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.08 mg/mL (5.95 mM); Clear solution
• Availability: In-stock

Source

Original product source