Propiolamide is a monooxygenase ( MMO ) system activator and glutathione peroxidase 4 ( GPX4 ) inhibitor. Propiolamide induces ROS production through interaction with the MMO system. Propiolamide promotes the accumulation of intracellular cytotoxic lipid peroxides and induces ferroptosis . Propiolamide induces programmed cell death via the apoptosis pathway. Propiolamide can be used in cancer research.
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