Desfesoterodine (PNU-200577) is a potent and selective muscarinic receptor ( mAChR ) antagonist with a K B and a pA 2 of 0.84 nM and 9.14, respectively. Desfesoterodine is a major pharmacologically active metabolite of Tolterodine (PNU-200583; HY-A0024) and Fesoterodine ( HY-70053 ). Desfesoterodine improves cerebral infarction induced detrusor overactivity in rats.
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