Quetiapine hemifumarate

Quetiapine hemifumarate
  • CAS No.:111974-72-2
  • Grade:99.96%
  • Formula:C23H27N3O4S
  • M.W.:441.54
  • Solvent:≥ 2.5 mg/mL (5.66 mM); Clear solution

Overview

Quetiapine hemifumarate is a 5-HT receptors agonist with a pEC 50 of 4.77 for human 5-HT1A receptor . Quetiapine hemifumarate is a dopamine receptor antagonist with a pIC 50 of 6.33 for human D2 receptor . Quetiapine hemifumarate has moderate to high affinity for the human D2 , HT1A , 5-HT2A , 5-HT2C receptor with pK i s of 7.25, 5.74, 7.54, 5.55. Antidepressant and anxiolytic effects.

Application

Products | Products > Disease Areas > Depression | Products > Disease Areas > Alzheimer's Disease | Products > Disease Areas > Obesity | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Lipid Metabolism | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > 5-HT Receptor | Products > Signaling Pathways > Dopamine Receptor

Product Information

  • Catalog No.: HY-B0031
  • CAS No.: 111974-72-2
  • Molecular Formula: C23H27N3O4S
  • Molecular Weight: 441.54
  • Purity: 99.96%
  • Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
  • Solubility: ≥ 2.5 mg/mL (5.66 mM); Clear solution
  • Availability: In-stock

Source

Original product source


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