Zonisamide (AD 810) sodium is an orally active carbonic anhydrase inhibitor, with K i s of 35.2 and 20.6 nM for hCA II and hCA V , respectively. Zonisamide sodium exerts neuroprotective effects through anti- apoptosis and upregulating MnSOD levels. Zonisamide sodium also increases the expression of Hrd1 , thereby improving cardiac function in AAC rats. Zonisamide sodium can be used in studies of seizure, parkinson’s disease and cardiac hypertrophy.
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Neurological Disease | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Carbonic Anhydrase | Products > Signaling Pathways > Apoptosis
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