Milnacipran

Overview

Milnacipran is an orally active Serotonin ( HY-B1473A ) and Norepinephrine ( HY-13715 ) reuptake inhibitor. Milnacipran inhibits monoamine transporters, especially the norepinephrine transporter and the serotonin transporter ( K i values of 31 and 8.5 nM, respectively). Milnacipran inhibits pERK1/2 activation. Milnacipran has antidepressant, anxiolytic and analgesic properties. Milnacipran inhibits biting behavior in mice. Milnacipran can be used in the study of major depressive disorder, anxiety disorders, and neuropathic pain (e.g., fibromyalgia).

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Serotonin Transporter | Products > Signaling Pathways > PERK

Product Information

• Catalog No.: HY-B0168
• CAS No.: 92623-85-3
• Molecular Formula: C15H22N2O
• Molecular Weight: 246.35
• Purity: 99.69%
• Storage: Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (10.15 mM); Clear solution
• Availability: In-stock

Source

Original product source