CZC-54252 hydrochloride

CZC-54252 hydrochloride
  • CAS No.:1784253-05-9
  • Grade:98.44%
  • Formula:C22H26Cl2N6O4S
  • M.W.:541.45

Overview

CZC-54252 hydrochloride is a potent and selective LRRK2 inhibitor with IC 50 s of 1.28 nM and 1.85 nM for wild-type and G2019S LRRK2 , respectively. G2019S LRRK2 -induced human neuronal injury is attenuated by CZC-54252 hydrochloride with an EC 50 of ~1 nM.CZC-54252 hydrochloride has a neuroprotective activity.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Parkinson's Disease | Products > Signaling Pathways > Autophagy | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > LRRK2

Product Information

  • Catalog No.: HY-B0792A
  • CAS No.: 1784253-05-9
  • Molecular Formula: C22H26Cl2N6O4S
  • Molecular Weight: 541.45
  • Purity: 98.44%
  • Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
  • Availability: In-stock

Source

Original product source


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