Fipronil

Fipronil
  • CAS No.:120068-37-3
  • Grade:99.49%
  • Formula:C12H4Cl2F6N4OS
  • M.W.:437.15
  • Solvent:≥ 2.08 mg/mL (4.76 mM); Clear solution

Overview

Fipronil is a broad-spectrum insecticide effective against Lepidoptera species as well as thrips, locusts, ants, cockroaches, fleas and ticks. Fipronil selectively inhibits GABA receptor with IC 50 s of 30 nM and 1600 nM for cockroach and rat GABA receptors , respectively. Glutamate-gated chloride channels ( GluCls ), which are present in cockroaches but not in mammals, are sensitive to the blocking effect of Fipronil. Fipronil also induces apoptosis in HepG2 cells and promotes the expression of CYP1A1 and CYP3A4 mRNA in human hepatocytes.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Digestive System Inflammation | Products > Disease Areas > Alzheimer's Disease | Products > Disease Areas > Parkinson's Disease | Products > Signaling Pathways > Others | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Cytochrome P450 | Products > Signaling Pathways > Environmental Pollutants | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > GABA Receptor

Product Information

  • Catalog No.: HY-B0822
  • CAS No.: 120068-37-3
  • Molecular Formula: C12H4Cl2F6N4OS
  • Molecular Weight: 437.15
  • Purity: 99.49%
  • Storage: 4°C, protect from light, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
  • Solubility: ≥ 2.08 mg/mL (4.76 mM); Clear solution
  • Availability: In-stock

Source

Original product source


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