Nomifensine

Overview

Nomifensine ((±)-Nomifensine) is a potent norepinephrine (NE) and dopamine (DA) reuptake inhibitor. Nomifensine inhibits uptake of NE, DA and 5-HT in rat brain synaptosomes, with IC 50 values of 6.6 nM, 48 nM and 830 nM, and K i values of 4.7 nM, 26 nM and 4000 nM, respectively. Nomifensine has antidepressant and analgesic effects. Nomifensine is used in neurodegenerative diseases, compound addiction, and pain research.

Application

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Product Information

• Catalog No.: HY-B1110
• CAS No.: 24526-64-5
• Molecular Formula: C16H18N2
• Molecular Weight: 238.33
• Purity: 98.05%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (10.49 mM); Clear solution
• Availability: In-stock

Source

Original product source