Isoetharine (Isoetarine) is an orally active selective agonist of β-adrenergic receptors . Isoetharine is a catechol-like agent and catechol O-methyltransferase ( COMT ) mediates its methylation. Isoetharine can promote the production of cAMP which stimulates the relaxation of smooth muscle cells and can be used as an emphysema, bronchitis and bronchodilator.
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