DCDAPH (Compound 2c) is a novel smart NIRF probe for detection of β-amyloid ( Aβ ) plaques (λ ex /λ em =597/665 nm in PBS). DCDAPH shows high affinity for Aβ aggregates ( K i =37 nM, K d =27 nM). DCDAPH shows good blood brain barrier permeation and can meet most of the requirements for the detection of Aβ plaques both in vitro and in vivo.
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Amyloid-β
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