Ginsenoside Ro (Polysciasaponin P3; Chikusetsusaponin 5; Chikusetsusaponin V) exhibits a Ca 2+ -antagonistic antiplatelet effect with an IC 50 of 155 μM. Ginsenoside Ro reduces the production of TXA 2 more than it reduces the activities of COX-1 and TXAS.
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