Carnosol is a potent Ribosomal S6 Kinase ( RSK2 ) inhibitor that could be useful for treating gastric cancer , with an IC 50 of ~5.5 μM. Carnosol, a Nrf2 activator, increases the nuclear levels of Nrf2 and can promote the expression of heme oxygenase 1 (HMOX1).
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