Isofraxidin

Isofraxidin
  • CAS No.:486-21-5
  • Grade:99.94%
  • Formula:C11H10O5
  • M.W.:222.19
  • Solvent:≥ 2.08 mg/mL (9.36 mM); Clear solution

Overview

Isofraxidin, a coumarin component from Acanthopanax senticosus , inhibits MMP-7 expression and cell invasion of human hepatoma cells. Isofraxidin inhibits the phosphorylation of ERK1/2 in hepatoma cells. Isofraxidin attenuates the expression of iNOS and COX-2 , Isofraxidinalso inhibits TLR4 /myeloid differentiation protein-2 (MD-2) complex formation.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Respiratory Disease | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Urogenital Disease | Products > Disease Areas > Musculoskeletal and Skin Disease | Products > Disease Areas > Lipid Metabolism | Products > Disease Areas > Pulmonary Disease | Products > Disease Areas > Autoimmune Disease | Products > Disease Areas > Arthritis | Products > Disease Areas > Colorectal Cancer | Products > Disease Areas > Digestive System Cancer | Products > Disease Areas > Prostate Cancer | Products > Disease Areas > Urogenital Cancer | Products > Disease Areas > Liver Cancer | Products > Disease Areas > Pancreatic Cancer | Products > Disease Areas > Depression | Products > Disease Areas > Pain | Products > Disease Areas > Obesity | Products > Disease Areas > Lung Fibrosis | Products > Disease Areas > Rheumatoid Arthritis | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > ERK | Products > Signaling Pathways > COX | Products > Signaling Pathways > MMP | Products > Signaling Pathways > Toll-like Receptor (TLR)

Product Information

  • Catalog No.: HY-N0774
  • CAS No.: 486-21-5
  • Molecular Formula: C11H10O5
  • Molecular Weight: 222.19
  • Purity: 99.94%
  • Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
  • Solubility: ≥ 2.08 mg/mL (9.36 mM); Clear solution
  • Availability: In-stock

Source

Original product source


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