Xanthoplanine, isolated from theroot of Xylopia parviflora , fully inhibits the EC 50 ACh responses of both alpha7 and alpha4beta2 nACh receptors with estimated IC 50 values of 9 μM (alpha7) and 5 μM (alpha4beta2).
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > nAChR
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