Semilicoisoflavone B

Overview

Semilicoisoflavone B, an isoflavone, mainly derived from Glycyrrhiza uralensis Fisch.. Semilicoisoflavone B reduces amyloid β ( Aβ ) secretion by inhibiting β-secretase-1 ( BACE1 ) expression and activity. Semilicoisoflavone B decreases BACE1 expression mainly through increasing PPARγ expression and inhibiting STAT3 phosphorylation.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Amyloid-β

Product Information

• Catalog No.: HY-N1280
• CAS No.: 129280-33-7
• Molecular Formula: C20H16O6
• Molecular Weight: 352.34
• Purity: 99.90%
• Storage: -20°C, sealed storage, away from moisture and light * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
• Solubility: ≥ 1.25 mg/mL (3.55 mM); Clear solution
• Availability: In-stock

Source

Original product source