Seneciphylline

Overview

Seneciphylline is an orally effective hepatotoxic inducer. Seneciphylline is metabolized by CYP450 enzymes into active intermediates, which covalently bind to intracellular biomacromolecules such as proteins and DNA to form adducts, which in turn trigger a series of toxic reactions, such as inducing cell apoptosis and damaging mitochondrial function. Seneciphylline can be used in hepatotoxicity research [1] [2].

Application

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Product Information

• Catalog No.: HY-N1282
• CAS No.: 480-81-9
• Molecular Formula: C18H23NO5
• Molecular Weight: 333.38
• Purity: 99.93%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 0.77 mg/mL (2.31 mM); Clear solution
• Availability: In-stock

Source

Original product source