Taraxinic acid can be found in the roots of Taraxacum flavostylum and Taraxacum lucidum . It is a Tyrosinase inhibitor that dose-dependently inhibits Tyrosinase activity, showing approximately 54.5% inhibition at a concentration of 50 μg/mL. Taraxinic acid has an IC 50 of 83.2 μM against melanoma cells A375 and HTB140, and an IC 50 of 60.4 μM against melanoma cells WM793, with activity being both dose- and time-dependent. Taraxinic acid holds promise for research in the field of anticancer therapy.
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